Drug Metabolism Prediction



Johannes Kirchmair, Raimund Mannhold, Hugo Kubinyi, “Drug Metabolism Prediction”

2014 | pages: 538 | ISBN: 3527335668 | PDF | 14,5 mb

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists.

The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey their expert knowledge distilled from many years of experience in the field. In addition to the fundamentals, computational approaches and their applications, this volume provides expert accounts of the latest experimental methods for investigating drug metabolism in four dedicated chapters. The authors discuss the most important caveats and common errors to consider when working with experimental data.

Collating the knowledge gained over the past decade, this practice-oriented guide presents methods not only used in drug development, but also in the development and toxicological assessment of cosmetics, functional foods, agrochemicals, and additives for consumer goods, making it an invaluable reference in a variety of disciplines.

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